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As per title. After a few hundred turns the game gets really slow. It's not too noticable on the global map but switching through views (tech tree, tactical combat, etc) takes a lot of time and the game is prone to crash.

Savegames get bloated to ridiculous sizes also (hundred Mb). While it in itself isn't a problem obviously I think you should take a look at how you store and manage your data because it makes playing longer games impossible.